All other applicants please call (865) 215-2385 and ask to speak to a supervisor for instructions regarding your situation. Military Personnel, former Knox County Residents and Lien holders making Application for Replacement Titleby mail for Certificate of Duplicate Title: Please mail your completed application to: Knox County Clerk, 300 Main St., Room 233, Knoxville, TN 37902. Please bring the damaged document with you as it must be attached to the application for replacement title. Such damaged titles must be replaced at the County Clerk’s office. Lien holders must make payment by check drawn on their financial institution’s account others may submit a cashier’s check or money order in the amount of $14.00.Īlterations, erasures or white out invalidates Tennessee Certificates of Title. Submit a notarized Power of Attorney signed by owner(s) or lien holder designating, Knox County Clerk to sign the application. Person(s) making application must submit copy of driver license(s) or other acceptable forms of identification. Lien holders will need to sign and print the name of the lien holder and sign their name as the individual representative. If state record permits and if the data system does not indicate a lien, owner(s) will be issued a replacement title at the time application is made and appropriate documents submitted. If a lien is recorded against the vehicle, a discharge of lien must accompany the application. This application requires the owner(s) or appointed power of attorney to sign his/her name in the box designated (signature of certifier/owner or power of attorney). To obtain a replacement Tennessee motor vehicle title, owner(s) must complete all shaded areas of the Application for Replacement Title. You acquire the study materials, study, and then take an approved boating safety exam administered by an approved representative of the TWRA. Also, the registered owners, when applying, must present proof of ownership and acceptable forms of identification. The Tennessee mandatory boating education law is similar to the driver’s license law. We can issue duplicate titles in our office, but they are not same day titles. However, for the Clerk's office to issue a replacement title, the vehicle record must be in the State's computer system and eligible for replacement. Can we get a duplicate title in your office Yes. If there is not a lien on a vehicle, the owner(s) may replace a lost or damaged motor vehicle title by visiting the Knox County Clerk’s office. If there is not a lien on a vehicle the owner(s) may replace a lost or damaged motor vehicle title by visiting either the Courthouse or Bonny Oaks office. Reclassification as a Standard Business.Read through everything you need to know about regulations and so on with an extensive list of FAQs arranged by state.Ĭhoose the form samples for Tennessee Duplication of computer programs that you’re looking for, select a subscription, integrate with powerful resources, and have full access to more than 85,000 legal business documents arranged by state. Increase your document workflow by integrating with a powerful PDF editor and eSignature solution. Instead of searching for business templates one by one, get an entire bundle of relevant examples. Join the most extensive web-based library and enjoy the following advantages: Utilizing the library saves time and assists you focus on business targets rather than burdensome bureaucracy. The library of online samples is state-specific, which means every form is created according to the laws and regulations in your state and is reviewed by expert lawyers on a regular basis. US Legal Forms has been providing easy access to Tennessee Duplication of computer programs legal documents for more than 25 years. DESCRIPTION: A Duplicate Title is a title that replaces a lost, stolen, mutilated or defaced title. ![]() ![]() Therefore, if you are still wondering how to get a new title if lost via mail, be prepared to meet the following requirements: Submit a completed replacement title application. Operate your company responsibly using legal form templates for Tennessee Duplication of computer programs The steps to replace a car title by mail in TN are straightforward and involve the submission of the appropriate documentation and fee payments.
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![]() If you bond with her, Vetle warms up to romp in the snow as a sturdy Shire. If you see a sparkling ice horse, stand perfectly still! If you are quiet, you might see Vetle come to life. She stood in reverie for such a long time that she began to take on the features of an ice sculpture. “It’s no wonder that a winter traveler would choose to stop and rest here,” she thought. Vetle found something magical about Jorvik, especially when it began to snow. She met a funny little penguin who became her best friend. Once upon a time, there was a very happy sleigh horse who dreamed of traveling the world, so when it came time for her retirement she did just that! She traveled west, south, east, and north. If you love a horse with a snappy and sweet (almost good enough to eat) temperament, you’ll be very happy to bond with Lebkuchen. They decided that they were happy enough to live ever after in Jorvik’s Winter Village, where Lebkuchen was even able to return to his old Lippi self on occasion. His companion, a gnome called Gumdrop, helped him remember the witch they encountered and the Gingerbread Spell she cast upon them. Mmm! Frosting!Īs many horses have done over the centuries, Lebkuchen made his way to the haven of Jorvik. As he struggled to gather his thoughts, a little gumdrop nose popped into view as a voice urged him to “macht schnell!” (hurry up!) He licked his forelock. Lebkuchen awoke in a dark German forest with a vague memory of a wizened old lady and her “tasteful” cottage. Hey, Starfam! Cool, sweet, and perfectly frosted-two magical horses trot their way into the Winter Village and will stay until January 10th! Silvergladeđ31đ99 Hillside construction side SilvergladeĒ02Ē01 SE of wheatfield Steveđ0 Rubiağorgotten Fieldsđ11Ē21 Up at gray dew Rubiağorgotten Fieldsđ20Ē26 Up around gray dew Rubiağirgroveē27đ61 Path to Aideen’s songĕ5 Rubiağirgroveē28đ51 Red string lower meadowĕ0 Rubia ValedaleĒ59ę3 Left of druid paddockē5 Rubia ValedaleĒ14đ03Ĝorner of path to MarioĒ0 Rubia Valedale Lakeē30đ41 Mountain passageđ0 ![]() Mossğorgotten Fieldsę1đ76ěehind rockformation facing Riding arena Mossğorgotten Fieldsđ18Ē27 Up around gray dew ![]() Mossğirgroveē37đ97 Under racetrack bridgeĔ5? Moss Valedale Lakeē41đ40 Right lower pathĕ0 Moss Hollow WoodsĒ27đ51 Near burned down summerhouseē0 Moss Hollow WoodsĒ49đ33 Raised fire placeĒ5 Moss Hollow WoodsĒ46đ15Ěbove bent near rune stoneđ5 Jute Valedale Lakeē26đ07 Left of waterfallđ0 Jute GreendaleĒ3Ē75 Paddock Island transport Juteğorgotten Fieldsĕ5đ78Ět coast near runestone Juteğorgotten Fieldsę5đ86ěeach opposite riding arena ![]() Juteğort PintaĒ33Ē59 Jetty under bridgeē5 Jute SilvergladeĒ51đ78 Right from the bridgeĒ0 Jute Valedale Lakeē16đ30 Left of trailerđ5 Jute Valedale Lakeē41đ32 Right lower cornerđ0 Jute Valedale Lakeē28đ24 Opposite pick nick tablesĕ PackardĐĬhamomile Hollow WoodsĒ53đ06 Near second big treeĐĬhamomile ValedaleĒ34đ03Ět leaftree west of path to MarioĕĬhamomile Hollow WoodsĒ68đ59 Mill side near burned down summerhouseđ0Ĭhamomile Hollow WoodsĒ38đ54Ět burned summerhouseđ0Ĭhamomile Hollow WoodsĒ38đ47Ět burned summerhouseđ5Ĭhamomile SilvergladeĒ21đ86ěetween three trees near BarneyĒ0Ĭhamomile ValedaleĒ47Ę7 Right side of druid paddockē5Ĭhamomile SilvergladeĒ08đ56Ğdge of Hollow Woods North of pathĔ0ĬhamomileğirgroveĒ75Ē00 Near three treesĬhamomile Silvergladeđ50đ26 Left of race trackĬhamomile Silvergladeđ91đ29ěelow balloonsĬhamomile SilvergladeĒ08đ36Ğdge of Hollow WoodsĬhamomile Silvergladeđ84Ē17 South of castleįlax Silvergladeđ41đ46Ğnd of the vineĐįlax Silvergladeđ86đ61Ğast of balloon at sheepđ5įlax Greendaleē3Ē73 Tiny mill center islandĕ5įlaxğorgotten FieldsĘ1đ73 Near white flowersįlaxğort PintaĒ28Ē36ěehind pony champįlax Silvergladeđ63đ62 West of Marley’s fieldįlax Silvergladeđ68đ74ěehind Marley’s paddockįlax Silvergladeđ88đ74 North of villageįlax SilvergladeĒ14đ24Ĝorner of Everwind fieldsįlax FirgroveĒ79Ē34 Near donkeys wallĐ There are a few more we have not listed yet but this are our findings so far on the spawn times per location.īee balm South HoofĒ28ē51ěetween the f and Pđ0īee balmğirgroveĒ70Ē06Ět triangle roadsĒ5īee balmğirgroveē03Ē02 Near coop jumps at sandpitĕ0īee balmğorgotten Fieldsę1đ70 Top right corner FFīee balmğorgotten FieldsĖ5đ85Ěbove lowered treeīee balm Greendaleė6Ē41 GED Goldspur Sunflowersīee balm Greendaleē4Ē36ěehind Sunfield farmīee balm Silvergladeđ80đ51Ět two treesīeebalm South HoofĒ61ē83 Under the nsđ5Ĭhamomileğirgroveē46đ70Ět Mrs. ![]() Add a generous amount of ice to your glasses. Pour your Celtic Sea Salt onto a small plate. Strain into a coupe or rocks glass with ice, salt rim optional. Agave Margarita Run a slice of lime around the rim of the glasses. Combine everything in a cocktail shaker, add ice, and shake vigorously for 15 seconds.agave syrup (equal parts agave nectar and water) Making an agave margarita is easier than you think and with just four ingredients, there’s no reason why you can’t make it at home. Play around with this fresh margarita recipe to find your happy. As someone who likes a more spirit-forward margarita, my go-to recipe is: Ingredients Like a half shot glass of lime juice or a small drizzle of agave can really make a difference. There are a lot of riffs and variations of the popular cocktail ( frozen margarita pie, anyone?), but as long as you have a shaken drink with tequila, lime, and orange liqueur, you are safely in Margaritaville. The basic recipe- tequila with triple sec and fresh lime juice-is forgiving for beginners but has enough room for experimentation that seasoned pros can add their own touches of flair. ![]() Like the venerable daiquiri, the drink is primal enough that it can be made from commonly found ingredients yet has enough complexity to offer endless possibilities for riffing and customization. Unlike many overly sweet store-bought mixes, a classic margarita is a strong sweet-tart drink with only three simple ingredients good-quality tequila, orange liqueur, and freshly-squeezed lime juice. You can serve this on the rocks or up, but if you serve it up, the strength. This margarita recipe is pitcher perfect The simple 2-1-1 margarita ratio is as easy to make by the glass as it is by the batch for a crowd. Making this beauty of a margarita recipe is as simple as the number of ingredients: 2 parts Tequila, 1 part agave nectar, and 1 part lime juice.A traditional margarita recipe is special in the pantheon of classic cocktails. Add ingredients to shaking tin and shake hard for 10 to 12 seconds. What's more, we dilute the agave syrup with just the amount of water for you (hence the "cocktail ready" part).Put good in, get good out. The agave for both the tequila and the agave nectar are organic and come from a single provider in the tequila Valley dedicated to quality. 3oz Fresh Victor Mexican Lime & Agave 1.5-2oz blanco or reposado tequila Directions. We did say we need the best ingredients right? Well, we don't like to be boastful, but we do think our margarita recipe ingredients are pretty great. Tres Agaves Cocktail Ready Agave Nectar.fresh lime juice 3/4 cup 2 tablespoons agave nectar 4 cups ice or. Tres Agaves 100% de Agave Organic Tequila orange liqueur we used triple sec (1/2 cup) 6 oz.So what does this leave us with? A few very simple things: From our point of view, the triple sec can add too much sweetness, without providing the necessary balance of tartness and acidity. You see the Tres Agaves Fresh Margarita recipe leaves out the orange-flavored Triple Sec, which is a staple of so many a recipe for a margarita. But maybe not all of the ingredients you expect. The best margarita recipe has to start with the best ingredients. But what is the best margarita recipe? Well, that does somewhat depend on your individual taste, but we think we have an answer. There are lots of recipes for a margarita out there in the world. On macOS there are many system-defined standard menus, like the Services and ![]() Here are some notes on making your app's menu more native-like. MacOS has a completely different style of application menu from Windows and Menu objects also have the following properties: ems Ī MenuItem array containing the menu's items.Įach Menu consists of multiple MenuItems and each MenuItemĪn example of creating the application menu with the simple template API:Ĭonst Ĭonst menu = Menu. Event: 'menu-will-close' Įmitted when a popup is closed either manually or with menu.closePopup(). Event: 'menu-will-show' Įmitted when menu.popup() is called. Note: Some events are only available on specific operating systems and are Objects created with new Menu or returned by Menu.buildFromTemplate emit the following events: Inserts the menuItem to the pos position of the menu. Returns MenuItem | null the item with the specified id menu.insert(pos, menuItem) menu.append(menuItem) Īppends the menuItem to the menu. ![]() browserWindow BrowserWindow (optional) - Default is the focused window.Ĭloses the context menu in the browserWindow.Pops up this menu as a context menu in the BrowserWindow. callback Function (optional) - Called when menu is closed.Only provide values you receive from other APIs or leave it undefined.Ĭan be none, mouse, keyboard, touch, touchMenu, longPress, longTap, touchHandle, stylus, adjustSelection, or adjustSelectionReset. It is not recommended to set this value manually, sourceType string (optional) Windows Linux - This should map to the menuSourceType.positioningItem number (optional) macOS - The index of the menu item toīe positioned under the mouse cursor at the specified coordinates.y number (optional) - Default is the current mouse cursor position.x number (optional) - Default is the current mouse cursor position.window BrowserWindow (optional) - Default is the focused window.The menu object has the following instance methods: menu.popup() You can also attach other fields to the element of the template and they will become properties of the constructed menu items. Generally, the template is an array of options for constructing a template (MenuItemConstructorOptions | MenuItem).Usually you would use theįor more information on macOS' native actions. This is used forĮmulating default macOS menu behaviors. Sends the action to the first responder of application. Instance properties can stillīe dynamically modified. Note: The returned Menu instance doesn't support dynamic addition or Returns Menu | null - The application menu, if set, or null, if not set. It contains standard items such as File, Edit, View, Window and Help. Note: The default menu will be created automatically if the app does not set one. This has the additional effect of removing the menu bar from the window. Passing null will suppress the default menu. ![]() For example, &File would result in &File displayed on the button label. ![]() In order to escape the & character in an item name, add a proceeding &. Underline, and the & character is not displayed on the button label. The indicated character in the button label then gets an &File for the file menu would result in a generated Alt-F accelerator that Indicate which letter should get a generated accelerator. Menu will be set as each window's top menu.Īlso on Windows and Linux, you can use a & in the top-level item name to Sets menu as the application menu on macOS. The Menu class has the following static methods: tApplicationMenu(menu) Create native application menus and context menus. ![]() Brooklyn Decker is a model and an actress. “I was living in New York at the time and my now-manager said to me, ‘You have no friends, all your friends are in North Carolina where you grew up and why don’t you call this guy, I hear he’s really nice.Personal Life: Affair, Girlfriends, Wife, KidsĮxcited to know the personal life of this brilliant tennis player? Andy Roddick started dating Brooklyn Decker in 2008. The Roddick-Decker household, as per Decker's account, has one person to say thanks to – her manager. However, as we can see now, the pair worked out in the end. “I thought it was very shady as one would and I did not call him back for five months.” Understandably, Decker was negatively surprised and told the Tennis Channel this about the story of how the couple met: Rather than approach her directly, Roddick actually got his attorney to contact Decker's agent. According to Decker herself, Roddick noticed her in a show she hosted for Sports Illustrated. She did not end up getting the award, but it must have been discouraging.Īs far as the relationship between Andy Roddick and Brooklyn Decker, it did not have a very romantic start. Unfortunately for the Ohio-born model, Decker's work in movies was not really recognized, as she earned three Razzie Award nominations for her roles in Just Go With It, What to Expect When You're Expecting, and Battleship. In terms of movies, she was not that active and did not have huge roles. Her most famous role is part of the main cast of Grace and Frankie, a now-seven-season show that ended last year on Netflix. When it comes to other work, Brooklyn Decker started working more and more in TV series and movies after she and Roddick got married. Due to her interest in sports, which is obvious, it was somewhat logical that she would end up dating and marrying an athlete. She also discussed the 2010 NCAA tournament for Sports New York. It all started with a few shows where Decker discussed NFL games of the week with Paul Zimmerman. During that time, she was one of the most popular young models, but she also went into the world of TV and movies. Before that, however, Brooklyn Decker was featured in the likes of FHM, Cosmopolitan, and Teen Vogue, while also appearing on the covers of GQ, Esquire, and Glamour, to name a few. ![]() Her work in modeling was exceptional, with the highlight being chosen as the 2010 Sports Illustrated Swimsuit cover model. Little did Brooklyn know that she would start a career that will span decades at this point. Her first notable work was for Mauri Simone, a brand that made prom dresses. During her time in the suburb of Charlotte, she finished high school and was subsequently noticed by a talent agency. She spent much of her childhood relocating, from Kettering to Middleton, then leaving Ohio to go to Matthews, North Carolina. They have a great story of how they met, but before the part of the couple meeting each other, it is worth looking over the life of Brooklyn Decker prior to meeting and later marrying Andy Roddick.īrooklyn Decker was born in a small city outside of Dayton, Ohio. Their marriage has largely been out of the public eye, but it is definitely interesting to see how they developed their relationship over time. Since then, they were able to build a family together, with their son Hank, born on September 30, 2015, and daughter Stevie, born on November 27th, 2017. Andy Roddick's wife: Brooklyn DeckerĪndy Roddick and Brooklyn Decker started dating in 2007 and tied the knot in 2009. On that note, let's look at Andy Roddick's wife, Brooklyn Decker. A large part of that success has been his fairly peaceful personal life. ![]() Despite his shortcomings outside of the one US Open title, Roddick is still one of the most successful tennis players of all time, even holding on to the number one spot on the ATP list. He is most known for his intense rivalry with Swiss legend Roger Federer, who denied Roddick four more Grand Slam titles in his career. Roddick is a legendary player that won over $20 million in tournament prizes, won one US Open, made three Wimbledon finals, and four Australian Open semifinals. Andy Roddick is an American former tennis player. ![]() How to Fix the XAMPP Error “Apache Shutdown Unexpectedly” in macOSĭepending on what version of macOS you’re running, you may already have Apache installed on your computer. That’s it! Your port numbers will be updated and Apache should now run without error. After Apache has been stopped, click the Start button to complete the restart process. You can do this by clicking on the Stop button along the same Apache row. Once you’ve updated the settings in both files, the final step is to stop Apache. ![]() When you’re finished, remember to save and close the file. Once you find it, you can go ahead and change it to “”. Next, search the file for the next instance of “443”. ![]() Locate “Listen 443” and update this to “Listen 4433”. When the file opens in your text editor, press Ctrl + F, and then enter 443 in the search field. To do so, you can return to the XAMPP control panel, then select Config under the Apache settings again. Now it’s time to move on to the second file. Step 3: Update the Default Port Settings in the nf File When you’re finished, save and close the file. Once you find it, modify it to “servername localhost:8080”. Once the port setting is updated, search for “Listen 80” and update it to “Listen 8080”.įinally, search for “servername localhost:80”. Locate “Port 80” and change it to “Port 8080”. This will display all instances of the number 80 in the file. To get started, press Ctrl + F, then enter “80” in the search field: The Apache nf file in Windows. Within this file, there are three settings you’ll want to update. Once you do, the file will open in your computer’s default text editor: The Apache (nf) file in XAMPP control panel. Step 2: Change the Default Port Settings of the nf Fileįrom the menu of files, click on Apache (nf). We’re going to be editing two of these files, starting with nf. This will open a drop-down menu of files. In the “Apache” row of options, click on the Config button. Since this error is related to Apache, we’ll focus on those settings. From here, you can update the configuration settings for the server stack. The first step is, of course, to launch XAMPP. Step 1: Open the Configuration Settings from the XAMPP Control Panel If you’re using a Windows device, you can follow these four steps to update your default port settings in XAMPP. How to Fix the XAMPP Error “Apache Shutdown Unexpectedly” in Windows Get started with DevKinsta today, even if you’re not a Kinsta customer. Looking for a free and powerful local WordPress development tool? DevKinsta features quick and easy site creation, email and database management tools, one-click PHP version switching, and full integration with MyKinsta. We will provide instructions for both operating systems below, starting with Windows. Also, the interface may look a bit different depending on the XAMPP version you’re using. However, the method for resolving the error varies slightly between Windows and macOS. In any event, the easiest fix is to simply modify the XAMPP default settings. Additionally, you may notice that the error message indicates the problem may also be attributed to “missing dependencies, improper privileges, a crash, or a shutdown by another method.” Usually, it means that another application installed on your computer, such as Skype, is using the same port as XAMPP. This message is most commonly caused by a blocked port. ![]() However, what may be new to you is the “Apache shutdown unexpectedly” error you’re seeing. If you’re reading this article, we’ll assume you’re already at least somewhat familiar with XAMPP. You can use XAMPP without having to upload your site’s files to your web hosting service. This means that if you are building a website, you can install WordPress locally on your computer. It runs PHP and Perl scripts, and is used to develop and test dynamic websites on local machines. XAMPP is a free, open source server stack that includes the Apache server and MariaDB database: The XAMPP website. An Introduction to the XAMPP “Apache Shutdown Unexpectedly” Error ![]() The dead soldier at the forefront of Alfa no longer has a CAC A and only a Glock 17. In update Beta v.1.8.2, these cards are a good source of Plastic in the Recycler.Īs of the current version, only Bunker Alfa and Bravo can be accessed. Well, maybe not that nice.The key cards needed to gain access to the bunkers.Ĭontrolled access card to top-secret bunker located nearby.Ĭontrolled card access card to top-secret military bunker. Like eating a massive bar of chocolate whilst lying on the beach and a hot naked lady fanning you with a giant feather. Thanks once again for reading, I am always surprised on how many people have been reading my blog and it’s a nice feeling. Let me know your ideas, thoughts and go wild with your imagination on what it could possibly involve! But with the way that the location is described and set out, I can’t really think of any other function that it may have. Remember that game? That was awesome for 1 month). There is one other way it may function and it could be a style of “King Of The Hill” where a Clan owns the location and others can challenge it if they think they are tough enough. The Loot that you get will be what is dropped by the other players or there may be some kind of reward system for the winner of the fight. This is all speculation, but, I am guessing that this will be used as some kind of “Battleground” where you meet up with rival clans to fight one another. There are a few resources to get here but nothing else to be had. When you tap on the Pump it says that “You need to join a Clan to enter this place” and the threat is showing ? as well as the loot. ![]() And the ploobis and grumbo are shaved away.) floating above it. Firstly you’ll notice that it has a Red Plumbus (The blamfs rub against the chumbles. The final place that we can see on the map but can’t quite reach is the “Pump Jack” (hehe, funny name again.) Now this is an interesting and mysterious zone that I have no real idea on how it will function. But then again, they already have the “Grading” of zones with Green, Orange and Red. It only makes sense that as you level up and have access to better vehicles etc, that the zones scale in difficulty. These are pretty much going to be the same as the Pine locations but, surprise surprise, will be Oak instead! I know right, who would have thunk it! I’m assuming that this in turn may bring along new enemies as well as stronger ones. ![]() The next Zones on the map that we can’t get to just yet are the Oak Bushes and the Oak Grove. To be honest, I’d be happy with any of my ideas to be implemented. I’m not exactly sure why they have decided to make the towers glow an luminous green colour maybe its covered in Kryptonite? Maybe there’s a shit tonne of Uranium there? Maybe Slimer has exploded and covered the whole thing in Ectoplasm? We’ll never know until we have access. I doubt you’ll have to scale the tower and commune with an eagle to do it, but who knows! I think that when the Devs are going to be updating the game further, they’ll chuck a Watchtower to the far East of the map so that we can unlock more. There are two identical (as far as I can tell) places on the map that we can’t get to on the map yet, The Watchtower! These appear to be locations with a bit of loot and resources, however their main function is to allow more access to the map! If you tap on one of them, there is a small bit of blue writing that states “Visit a watchtower to unlock vision in this sector.” Now it seems like they are going all Assassin’s Creed on this shit and you have to unlock more of the map by going here. (See, I’m not the god of LDOE, I am a mere mortal like you and still learning!) This is something that I didn’t know until recently. For Bunker Charlie you will need the Helicopter and to be able to reach the Zones across the river, you’ll need the ATV. One thing that I was informed about recently (thanks to on reddit) is that when you tap on a location that you cannot reach, in the bottom right hand corner it states “Transport Required.” If you tap on this it will take you to the Crafting Screen and show you what transport you need to build to be able to get there. There are quite a few places that are actually shown on the map that we can’t get to, stop teasing us you naughty Devs! But I am sure that as the updates keep slowly trickling through, we’ll get further access to them. This is something that I would also like your opinions on, so feel free to leave a few comments at the end of the blog! This is mostly going to be conjecture (yes I know big words, me smart) but I think it’ll be at least worth looking into and exploring. Today we’ll be looking at the places on the map that we currently cannot get to and what they could possibly add or mean to the game. ![]() Treatment for brain cancer for other patients.”įor animal owners interested in exploring clinical trials, Dr. “Her owner is committed obviously not only to Fiona’s health, but also to contributing to medical research in general and advancing the “Fiona makes this possible because Fiona’s owner makes this possible,” says Dr. Dow says that this kind of valuable medical research would not be possible without dedicated owners like Michelle. Pediatric bone cancer trials, so we’re hopeful that the brain cancer work that Fiona’s a part of will also lead to treatments for kids with brain cancer.”ĭr. Steven Dow, Board-certified Veterinary Internist and head of the clinical trial. ![]() “The trial Fiona is a part of actually came out of our work with bone cancer in dogs,” explains CSU Professor Dr. Gliomas are one of the most common brain tumors in children, and researchers are hopeful that the vaccine Fiona received can one day be used to treat She’s responded so well to the treatment.”įiona’s success is not only promising for veterinary medicine, but for human medicine as well. Since her original diagnosis, which is absolutely incredible. “Fiona’s case stands out primarily just because she has had such a great success,” says Breonna Kusick, Neurology Clinical Trials Coordinator at CSU and one of Fiona’s biggest fans. It’s safe to say that Michelle never expected that after receiving her first vaccine in July of 2019, Fiona would still be enjoying a happy and active life nearly three years later. "We’re hopeful that the brain cancer work that Fiona’s a part of will also lead to treatments for kids with brain cancer." To giving Fiona her best possible chance at a longer life, despite not knowing how much more time she would get. Though it was a significant commitment for Michelle and a long trip to make each month, she was dedicated Once it was confirmed that Fiona’s tumor was indeed a glioma, she began receiving the vaccine via injection during monthly visits to the FACC. She and the team at the FACC were hopeful that by participating in the study, Fiona would survive beyond her initial prognosis while contributing to the future of treatment for dogs with “We decided to go ahead and enroll,” Michelle says. The trial would test a tumor vaccine that, when given in combination with other medications, researchers hoped would teach the body to attack cancer cells in glioma tumors. The clinical trial in question was developed at the Flint Animal Cancer Center (FACC) at CSU to study a potential new treatment for dogs with gliomas, which are a particularly aggressive type of brain tumor typically only treatable with radiation, surgery, “They said ‘we do have a clinical trial, if it is a glioma brain tumor, then we have this option,’” Michelle recalls. That’s when participation in a clinical trial was first suggested. Voss Veterinary Teaching Hospital, which was further from her home but well-equipped to treat Fiona.Īt her visit to CSU, Michelle met with a team of veterinary specialists to determine what Fiona’s treatment plan would be going forward. Reached out to the Neurology service at Colorado State University’s (CSU) James L. Knowing she didn’t have time to waste, Michelle “The median survival for gliomas that are untreated is about five weeks in dogs.” Even with treatment, dogs with gliomas typically survive only 3-12 months.ĭevastated by this news but ready to fight, Michelle planned to pursue radiation therapy but experienced a setback when the necessary equipment at a local specialty practice was down for maintenance. “Historically, gliomas carry a very poor prognosis,” Dr. She immediately took Fiona to a local specialty practice for an MRI, which revealed a tumor on the Boxer’s brain that was suspected to be a glioma. Having fostered and rescued dogs throughout her life, Michelle had been through multiple illnesses and diseases with her dogs before and knew about the availability Her journey started in 2019, when the then eight-year-old Fiona began to have seizures. ![]() "The median survival rate for gliomas that are untreated is about five weeks in dogs." “Most people can’t look at her and not smile,” her owner Michelle Beston says.Ĭonsidering how much joy Fiona radiates, you would never guess that she’s battling a serious form of brain cancer. The all-white Boxer is completely deaf, with one blue eye, one brown one and a permanent goofy grin. Rebecca Packer, Board-certified Veterinary Neurologist. “She’s just so happy and excited to see us,” says Dr. Fiona the Boxer is a bit of a celebrity at Colorado State University's Flint Animal Cancer Center. I really wish there was an extra helmet for Leia. The figures, for the most part, are nice. Despite the wing undersides and the closing canopy, it's a really nice set. Ok, maybe not that bad, but the most attractive way to display it will take a lof of clear bricks that are not included to make it display prettily. The underside of the wings are ugly, kind of like an inside out sausage. You see the underside of the wings when it is in the parked or resting position. With the wings up, the bloom sort of comes off the rose. With the wings down, it is a beautiful thing. I did not take a picture of the brick separator, but rest assured there is one. There were some extra pieces, including a cookie and a Thermal Detonator. Maybe I was disenchanted with this portion, because the cockpit canopy cannot stay open. ![]() Maybe it's the dark brown, or the weird paint details. The Han is nice, but Chewbacca's a little bit off. I don't know if I was tired by this point, or if the cockpit design just wasn't that inspired, but compared to the rest, it wasn't a terribly exciting finish. The wings weren't terribly complex, but they were time consuming due to size.īag 6: Probably the smallest and most disappointing of the bags. You make some panels for the body that pivot up and down to reveal the interior of the shuttle. Plus, you get Princess Leia and her cookie.īag 5: This bag is the biggest one in the set because you are making the wings and finishing the body of the shuttle. The fin just slots right into the top before you pin it in place. It is solid, it is large and in charge, and take it from me, make sure you attach everything in the right direction so that the pin holes line up, because getting it back apart to fix a minor mistake is a giant pain. The bag finishes adding some details to the body, including guns.īag 4: The fin. You must flip this down in order the lower the ramp. The hatch I mentioned before has a piece on a hinge that will prevent it from lowering on its own. The landing struts are linked and will move up and down in tandem. I don't know why they went with the 2 2x4 tiles that will soon be hidden. If you look in the second image below, you can see the Technic Pin Connector (62462) that is used as the trigger to fire the missile.īag 3: The first thing I want to make note of is how cool and SNOT the engines of this ship are and how it's a whole panel that's attached to the back. They ratchet up and down individually and you fairly successfully disguise the spring missile shooters. You also create the attachment points for the moveable wings. There's a box with 2 Thermal Detonators (although if you want 3, the extra pieces are there), a weapons rack, and a hatch in the floor.īag 2: you're continuing to expand the structure of the shuttle's body. For this set, there are 6 numbered baggies, and a bag containing the instruction book and a sticker sheet.īag 1: Here you build the basic foundation of the shuttle and the 2 Rebel Troopers. Some people may wind up picking up a set that is open box or, want to verify the box contents before beginning a build. Han, Leia and the 2 Rebel Troopers are exclusive. ![]() There are 5 minifigures 4 of which are currently exclusive to this set. Chewbacca is available in this form in 2 other sets. ![]() This seems to be about average for pricing for a licensed set. At $99.99 the price per piece works out to a bit under $.11 each. This particular ship is a beautiful and elegant design in the films, but how does it look when translated in the most recent LEGO iteration? Well the box was pretty, so let's delve into the set.īefore we get to the build, let’s talk value. I never really realized how much I enjoyed stuff from Return of the Jedi until I really looked at my LEGO collecting habits. I've been wanting to build this set since it was released in June. ![]() Previous research has focused on physiological measures such as inflammation markers and the impact on inflammation-related illnesses such as arthritis (Buijze et al., 2019 Zwaag et al., 2020), altitude acclimatization (Buijze & Hopman, 2014), and the activity of the autonomic nervous system (Kox et al., 2012, 2014). These two components are complemented with exercises seeking to increase practitioners’ commitment, such as push-ups, stretching, and a reduced number of yoga poses (Innerfire, 2021), which are used to build the discipline for regular application of breathing techniques and cold exposure. Simultaneously, recent years have witnessed the uprising of the Wim Hof Method (WHM), a combination of pranayama-like breathing and cold exposure in the form of cold showers and, in its more extreme variant, ice baths. Hence, it is important to provide remedies that attenuate this downward spiral. Other adverse consequences include depression (Spada et al., 2008), anxiety (Shi et al., 2020), increased levels of inflammation, and a heightened risk of cardiovascular disease (Black & Garbutt, 2002 Richardson et al., 2012). Experience of stress is associated with a variety of negative outcomes such as a neglect of physical exercise, increases in drinking and smoking, and the adoption of an unhealthy diet in terms of high fat intake (Leventhal et al., 2017 Mikolajczyk et al., 2009 Ng & Jeffery, 2003 Vidal et al., 2018). This subjective evaluation is a relevant part of an individual’s response to stress (Cohen et al., 1983). Perceived stress is a widely employed notion to capture individuals’ subjective stress experience (Cohen, 1988 Fliege et al., 2005 Roberti et al., 2006 Taylor, 2015). Stress is a major concept regarding individual health. Combinations of breathing techniques and cold exposure may be employed to decrease individuals’ perceived stress. The breathing technique and cold exposure on their own were not found to yield substantial effects, indicating synergies between both exercises. The combined group exhibited a medium to large positive effect on perceived stress compared to the control group. ![]() The instruments exhibit a substantial correlation (r = 0.842, p < 0.001). Perceived stress is measured employing the 10-item version of the Perceived Stress Scale (PSS-10) and the 20-item version of the Perceived Stress Questionnaire (PSQ). Eighty-six individuals participated in the study. An experiment involving four groups was conducted, yielding separate cells for breathing technique-only and cold exposure-only, as well as a combined treatment and a control group. A pranayama-inspired breathing technique, cold exposure, and their combined application were assessed for their potential to reduce perceived stress in adults and compared to a control group. |
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